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Spectral Confocal Microscopy

A2. Confocal Achucarro Basque Center for Neurosciences - Imaging Facility Leioa
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Equipment
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Technical Resources

Description

Optical sectioning techniques that reject out-of-focus light to generate high-resolution 3D images.

How this lab uses this technology

Spectral confocal microscopy enables high-resolution, high-contrast imaging by rejecting out-of-focus light and separating the emission spectra of multiple fluorophores. This technology supports advanced multicolor analysis, discrimination of overlapping signals, and three-dimensional reconstruction of complex biological samples, making it particularly suitable for in-depth cellular and tissue studies.

Equipment

Notes

- Vesicular Rps6 Released by Astrocytes in an Experimental Model of AD Regulates Local Translation and Enhances Synaptic Integrity in Neurones. Journal of extracellular vesicles, december 2025 - Disruption of hnRNP A2-mediated RNA dynamics by amyloid-β drives MBP increase in Alzheimer’s disease. Cellular and molecular life sciences, august 2025 - BirthSeq, a new method to isolate and analyze dated cells in different vertebrates. Development, july 2024